Gefitinib is protein tyrosine kinase inhibitor of a selective EGFR, can block the signal transduction pathway of tyrosine protein kinase, and then promote tumor cell apoptosis.

吉非替尼为一种选择性的EGFR一蛋白酪氨酸激酶抑制剂，能阻断酪氨酸蛋白激酶信号传导通路，从而促进肿瘤细胞凋亡。

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CONCLUSION: CD117 can be regard as the related tumor antigen of MM, and may be a valuable marker in the use of tyrosine kinase selective inhibitors, which inhibit the signal conduct to the target.

结论CD 117可作为MM的肿瘤相关抗原，也可作为靶向信号转导抑制剂酪氨酸激酶选择性抑制剂应用的有价值的标志。

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Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.

目的探讨选择性及非选择性环氧合酶-2抑制剂（COX-2）对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。

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